Extent of infarct size and microvascular obstruction following unsuccessful reperfusion in patients with ST-segment elevation myocardial infarction
نویسندگان
چکیده
Background Impaired microvascular reperfusion (no-reflow) and unsuccessful infarct-related artery (IRA) revascularization are associated with a worse clinical outcome in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). Reperfusion can be identified by epicardial or microvascular flow determined by angiography as Thrombolysis in Myocardial Infarction (TIMI) flow grade and a myocardial blush grade (MBG), respectively. Moreover, microvascular obstruction (MVO) determined by CMR is also a well-known predictor of an unfavorable clinical outcome after STEMI. The aim of the study was to determine the effect of impaired reperfusion estimated by angiography on microvascular obstruction and infarct size (IS) measured by CMR.
منابع مشابه
Evaluation of infarct size and microvascular reperfusion on angiography and cardiac magnetic resonance in patients with ST-segment elevation myocardial infarction
Background Impaired microvascular reperfusion (no-reflow) and unsuccessful infarct-related artery (IRA) revascularization are associated with worse clinical outcome in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). Successful reperfusion can be estimated by epciardial and microvascular flow. Both of them can be ev...
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Background Cardiac MRI (CMR) provides unique characterization of myocardial injury post acute ST-Elevation Myocardial Infarction (STEMI). It is the gold standard for non-invasive measurement of Infarct Size (IS) and tissue perfusion during STEMI. Microvascular obstruction describes suboptimal tissue perfusion despite restoration of flow in the infarct-related artery (IRA). IS and MVO are indepe...
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